One of the most flexible frames in the game, that shines at AOE clear.
Goes incredibly well with low Status Chance weapons as [Saryn]'s Toxic Lash(3) forces Toxin procs, increasing your DPS greatly.

If you want better weapon buffing swap [Augur Reach] for [Venom Dose].

Umbra Polarity for compatibility with PT build.

With the innate scaling of her Spores [Saryn] just doesn't need that much Strength to be effective. If her damage is too low to kill it ramps too slow to be effective anyway and you should just use weapons instead.

General-gameplay of an AoE clear goes like this: Cast Spores(1), spread Spores from targeted enemy, then cast Miasma(4). That will set off a cascade of spores, spreading Spores at a distance of up to 100.8m.
Spreading Spores is done by:
1. Hitting enemy with melee.
2. Hitting enemy with any weapon while Toxic Lash(3) is on.
3. Hitting the spores on the enemy body.
4. Killing enemy with non-Spore damage.
Killing an enemy with Spore damage normally doesn't spread the spores, but if the enemy is affected by Miasma(4) then that rule is ignored and Spores are spread anyway. This is what makes spores spread significantly longer than the range of the Spore ability would indicate.