Make sure you recast nourish when low on hp and nourish duration, mainly because of his viral buffing which is 72% on this build.
Use whatever weapon suits you I personally use [Felarx] corrosive cold from Ninjase, a 59% radiation, heat, and viral [Tenet Plinx] and [Vastilok] for stripping.
Yes his 4th does strip but it’s ability strip and it might get nullified but I you want to stay tanky as possible so vastilok corrosive heat armor strip is also useful

https://overframe.gg/build/328134/felarx/the-devastating-void-extreme-raw-damage-cold-corrosive-one-shot/

https://overframe.gg/build/268587/vastilok/vastilok-primer-armor-strip-viral-heat-status/

https://overframe.gg/build/395842/tenet-plinx/tenet-plinx-hybrid-primary-alt-fire/

And Exilus should be [Primed Sure Footed] or [Handspring]
Whatever floats your boat for the arcane slots
Can run helminth less or use gloom or blood altar