[Wisp] is a frame that needs a strong loadout (Primary, Secondary, Melee) if you want to have good results with her.
Main ability loop is going to be your 1st (Reservoirs) and 4th (Dispensary) - guarantees that you have health, fire rate, cc and energy at all times.
Use your 2nd (Wil-O-[Wisp]) and 3rd (Breach Surge) ability when you need to remove agro from you and debuff tanky units.
You will need to Umbral forma her, I believe she is one of those frames that no matter how you will build her she will always benefit from umbral mods.
Personal Loadout recommendations:
Primary - Kuva Bramma
Secondary - Kuva Nukor
Melee - [Kuva Shildeg]