Concept: Xata's Whisper can stack Overwhelming Attrition even if the initial hit is critical and/or applies status, thus we run Arcane Avenger, [Combat Discipline], 3 tauforged crimson archon shards providing secondary crit chance, and Cascadia Overcharge to push us over 200% crit chance (201.75% to be exact) and a lone augur set mod to generate, basically, permanent overshields. [Xata]'s Whisper also double dips headshot and faction multipliers, thus we run the evolution for increased headshot damage and a primed faction mod. This means we have one of the highest raw damage builds possible in all of Warframe. Pair it with a frame that can ignore the damage [Combat Discipline] does, has a super stable energy economy (especially with the archon shard loadout below), and that is incredibly durable, and you have yourself a winning formula. We further boost our damage by armor stripping and priming our target with our [Latron] Incarnon. The viral stacks gives us a WHOPPING 325% bonus damage to health, and the raw viral damage of our [Laetum] does 75% bonus damage to health...so lots and lots of ways to amplify our damage.

Archon Shards:
2 Amber Archon Shards: Energy Orb Effectiveness
3 Tauforged Crimson Archon Shards: Secondary Crit Chance

Weapons:
Primary: Latron Incarnon: https://overframe.gg/build/523415/latron-prime/armor-strip-latron/
Secondary: Laetum: https://overframe.gg/build/528393/laetum/xatas-whispering-laetum/
Melee: Praedos Mobility Statstick: https://overframe.gg/build/528433/praedos/mobility-statstick-praedos/

P.S. Run Zenurik to pair with the energy economy archon shards and maintain your ability to recast Mesmer Skin and [Xata]'s Whisper as needed, and use Enthrall when the target is stunned by Mesmer Skin so it doesn't cost any energy. Reave as you see fit to either regain a bunch of HP or 1 shot thralls. Always Enthrall the Acolyte ASAP. Also, the [Laetum] will easily kill ads, while [Xata]'s Whisper is active, all the way to level cap without needing to armor strip, making this the most comfortable way to overkill enemies at ANY level.