Voruna's 2 (currently - may be patched later) redistributes your average proc damage in an area, and applies 10 procs using this average.
Therefore, to effectively nuke, you have to apply the largest proc possible, and also let the first 10 procs dealt by [Voruna]'s 2 expire before the enemy dies.
I would recommend doing this with slash, since her 1 will force proc slash.
As an example, say you successfully get 10 slash procs on the first hit of the 2 (it has to be the first hit, otherwise it wont work - unless you let all the procs expire), which deal a total of 100 damage per tick. You then apply a 1M damage per tick slash proc. You now have 11 slash procs active.
Scenario 1: The enemy dies with the 11 slash procs.
Avg slash proc damage = (100 + 1M)/11 = 90.9k
Distributed damage: 10 procs * 90.9k = 909k
You deal slightly less damage per tick than your original proc. Still a lot, but not optimal
Scenario 2: The enemy dies with only the 1 high damage slash proc.
Scenario 2 can be difficult to pull off, so subsume Well of Life and use it to control the detonation. Well of Life will also prevent the enemy from dying on the first hit, before any high damage slash procs can be applied. So you can use this for low levels too.
You can use archon shards for casting speed and energy max, or you can remove [Pool Of Life] and replace with what you want.
For slash application, use [Voruna]'s 1 with a heavy attack [Fragor Prime]. Fragor Build
The Mecha set serves as a way to [Extend] the range of the nuke by 30m (+ some extra bugged behaviors that I won't go into). Since [Voruna] has invisibility, your Kubrow will last more than a couple of seconds. Vizier Build