Yes, another Heat + Viral weapon. Looking at https://warframe.fandom.com/wiki/Damage#Overview_Table, the combination of the physical damage types, Heat, and Viral seem to cover all factions acceptably. using [Primed Heated Charge] also allows [Archon Vitality] to be used on [Mesa] herself, further increasing status procs.

In theory, [Galvanized Shot] should produce better returns than [Hornet Strike], though testing will reveal how reliable it is. Five possible unique status procs x 120% weapon damage at three stacks of Galvanized Shot = +600% weapon damage. https://warframe.fandom.com/wiki/Galvanized_Shot#Damage_Multipliers

Build copied from: https://overframe.gg/build/320441/ after following comments from https://overframe.gg/build/1120/.