Energy Refund per hit let you spam Virulence and Larva and gaining stacks of Mutation even more quickly then in Configuration A. Lower strength means nothing in quicker missions and average duration (bit higher than in A) and range let you use every his skills efficiently, high survivability make him one of the best tank in game. And the best thing here is that he is getting better with every Stack he gain.
Thanks to [Insatiable] augment mod he stack Mutations much quicker what will let him be even more helpful for his team metes in missions like mobile defenses or excavations or even Exterminates. Pure fun!
I simply LOVE HIM for his amazing synergy between his skills. One of the best frame in game. [Nidus] is one of my favorite frames so I tested him in a lot situations... this build is ultimate solution for any troubles. And it's viable for any configurations. Which I'll give you of course.
This is my configuration B. A little bit weaker but more spam-able build for quicker missions.
Suggested arcanes are Grace & [Guardian].