Cast Accuse for CC (Crowd Control), cast [Gaze] for defense reduction (casting [Gaze] twice in the same area will make enemies entering the area of effect even weaker), combine both abilities with The Vast Untime to make enemies weaker to void damage, buff your weapons with void damage by casting [Xata]'s Whisper, & finally steal enemy weapons with Grasp of Lohk granting you more CC & damage output, then go to town on the enemies with your fave melee/gun!
Pay attention to durations, particularly Accuse & The Vast Untime. Utilize [Rolling Guard] when your shield breaks as this will give you a moment to [Recover]!
In the case of fighting infested enemies it may be wise to bring [Quick Thinking] in place of [Rolling Guard]!

HAVE FUN!