Arqubex has the highest technical dps potential of any weapon the the game currently. However, it is also an arch gun, which has limited mod potential and synergies thanks to [Voidrig] being the only way to use it. Nevertheless, it still functions great as it pretty much just destroys anything and everything.
Note: a Use primed [Dual Rounds] instead of the normal, overframe hasn’t updated it yet
Since you can’t aim with Arqubex, [Critical Focus] and [Marked Target] are completely useless.
I built radiation just for enemy Necramechs and the Murmur units as well as for Eidolons but you can change the elements as you wish for other enemies. (Although it probably wont matter since [Arquebex] does an insane amount of damage already)
Side note: Despite the great dps of this weapon, enemies with high damage attenuation will appear a lot more tankier when hit with the [Arquebex]. Keep that in mind when doing public missions and someone decides to bring out their [Voidrig].