Possibly and probably the best weapon in the game to just speed run missions, wiping entire rooms instantly.
Toxic Progenitor is generally preferred so you can use just Primed Cryo Rounds to get Viral, if you've got Viral sorted elsewhere opt for Cold Progenitor instead
Bladed Rounds is technically better than Heavy Caliber for DPS but the inaccuracy creates better AoE from your shots and you don't have to aim down sight with it.
If you're willing to sweat it then Galvanized Scope is good damage, not only benefitting Hunter Munitions but being a straight damage upgrade to Heavy Caliber anyway. The altfire can make getting stacks a lot easier but I don't think the weapon particularly needs extra damage and if you were looking to go long in missions then Buff abilities are gonna have a much bigger impact such as Roar.
If you're opting out of Bane mods Bladed Rounds is your next best mod, Hammer Shot is also nice for more Viral procs.
Ammo pickup of 1 = having any ammo mutation at all is all you need, use [Ammo Drum] if using any ammo support.