This build has been tested in steel path survival of an hour long.
The true joy of this build is it allows you to move around the map. stacks are still important yes but you no longer need to rely standing in his ult whilst tethered to an enemy to survive the wild world.
This build thrives when you have an alley to tether to.
Fire [Nidus]:
Between Arcane Grace and Niduses natural healing rate your health pool should be bottomless.
For solo play fire [Nidus] I would recommend switching augor [Stretch] for augor secrets for a bigger boost to health and fire damage to help armor strip enemies.
Ice [Nidus]:
An infinite wall of armor nothing can pierce his hide.
This is an ultra tank [Nidus] teher up and no matter what is sent at you it will not kill you.