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Combo
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Build Immolation to max heat by casting Inferno on ennemies or on nothing (it works too) then go in a crowd and cast:

3-4-1-4

Reset Immolation by disabling and re-enabling it to save energy pool if there's no other crowd of ennemies nearby. Wait the sparks and the DoT from Inferno to kill everything in range and collect energy orbs. Repeat.

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Combo explanation
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Cast 3 : to strip 100% armor
Cast 4 : while aiming at the largest area of ennemies to build Strength on the next cast with [Ember] passive
Cast 1: in the middle of the crowd to initiate the real damaging part of the combo
Cast 4 again: to start the apocalypse

Reset Immolation to keep the damage reduction bonus and save energy pool, collect energy orbs from fallen ennemies and repeat the process on the next pack of mobs.

Works best with Zenurik Energized Dash. Keep that buff alive at all time.

Dethcube sentinel with Energy Generator is much appreciated too.

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Sustainability
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The build is very sustainable with massive healing from [Healing Flame] and overshields from [Brief Respite] + huge damage reduction from [Adaptation], Arcane [Guardian] and the Immolation ability.
300hp is really no big deal here.