Hello, my English is bad, I hope to make myself understood. (Google traslator)
This would be the construction of "Eternal [Nidus]".
Preferably I try to prioritize skill strength and a decent range, I don't think the use of duration mods is necessary as skills have a good duration. Regarding efficiency, I prioritize using "Hunter's Wrath" to [Recover] energy from damage taken. I have used this construction for hours on a steel road and it has worked wonderfully for me.
Use: use the second ability when there are several enemies, then the first ability and you will see how the mutation charges rise quickly. If I'm going for the first few mutation charges, I use the second and launch the third at any enemy caught in the tentacles to avoid lethal damage. Once 25 mutations have been obtained, in case of receiving lethal damage, these are consumed thanks to the "[Abundant Mutation]" increase mod, the refresh time is moderately moderate. (I do not know if it is well written) The good part of the increase, 300 mutations are saved and it works as an exit key before a quick kill by high level enemies. Note: I prefer to have skill 3 always activated against enemies +200 level and skill 4 in case of having a drastic reduction in health.
As for the arcana, I use arcane grace and arcane [Guardian], to make it a little more tank and thus avoid dying quickly