This is meant as a Progression guide, using this build as a starting point and evolving on it as we get better mods throughout the game.
Baby's first Saryn build Good for enemies up to level 60 or so.
This build assumes that you've farmed Saryn's pieces from Kela De Thaym on Sedna and therefore completed the Second Dream and have access to Energizing Dash in spoiler mode.
A mod that can be "difficult" to get is Regenerative Molt, it comes from Red Veil or Steel Meridian.
You have to be max reputation level with them to unlock warframe augments. Which if you either A) want to farm yourself or B) You don't have friends to help you get one, can take a loooooooong time to get.
Power Range: Saryn's Number 1 most important stat! Power range affects the spread range of spores, the more enemies you have marked with spores the more damage you'll be doing and the faster it stacks. This will also affect Miasma's radius. Using Stretch and Augur Reach will give us enough range to get by for now.
Power Strength: Saryn's 2nd most important stat. This will effect the upfront damage of Spores, Toxic Lash and Miasma along with the healing ticks from Regenerative Molt. Right now all we have is Intensify which is a little lacking tbh. This will be upgraded in the next build
Power Efficiency: This is Saryn's 3rd most important stat. This lowers our energy costs across the board. We supplement 30% efficiency with Hunter Adrenaline(Gain energy upon taking health damage) and Energizing Dash from Spoiler Mode.
Defense: Saryn has decent defensive stats but nothing crazy, so we need to help her out as much as possible. Running Physique and Vitality will get our health pool rather large at a respectable 1k. Steel Fiber will make each health point worth more HP and Regenerative Molt will give us on-demand healing for 35 energy.
I tend to play melee focused, here's my Broken Scepter build for early/mid game.
Once finished here check out my next step on progression here